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Separate preclinical work examined BPC 157 as a therapy for disabled myotendinous junctions in rats (PMC8615275)

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Limitations include relatively short treatment periods (6 weeks per arm), potential carryover effects despite washout, modest sample size limiting power for subgroup analyses and exclusion of newer agents (e.g., tapentadol) and long-term safety outcomes, which may restrict applicability to broader clinical practice

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