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The blinding of subjects and researchers was reported in four studies (Reference Hashim, Anwar and El-Fatah22,Reference Nasr9,Reference Chandil, Pande and Sen27,Reference Gayatri, Kumar and Kumar28)

When expanding trial eligibility criteria to reflect broader patient populations typically encountered in clinical practice, we identified 453,201 individuals initiating semaglutide or sitagliptin (expanding SUSTAIN-6 eligibility) and 136,089 initiating tirzepatide or dulaglutide (expanding SURPASS-CVOT eligibility)

Share: Women and older adults taking the anti-obesity drug semaglutide may be at higher risk for muscle loss, but higher protein intake may help prevent muscle loss in these patients, according to a small study presented at ENDO 2025, the Endocrine Society's annual meeting in San Francisco, Calif