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It would be interesting to investigate a more extensive study population to assess the potential beneficial effects of CRWP in female children with ASD, as the manifestations of ASD can differ between males and females ( Conclusion In conclusion, this study demonstrated that nutritional intervention with CRWP effectively improved glutathione levels in children with ASD, ameliorated some behavioral domains impacted in ASD and was well-tolerated

The glutamate co-release of DA neurons expressing VGLUT2 drives the burst discharge of cholinergic interneurons, stimulates the nicotinic acetylcholine receptor at the end of DA neurons, and promotes DA/glutamate co-release, forming a positive feedback loop [167]