For example, the open-label mB12/LDFA study selected individuals with poor glutathione and methylation status to potentiate the ability of the treatment to change these parameters (James et al., Like the participants in the mB12/LDFA study, participants in the BH4 study demonstrated some less favorable biomarkers at baseline, but these biomarkers were related to chronic oxidative stress and inflammation
Our experienced medical professionals carefully screen each patient, perform thorough evaluations, and provide personalized recommendations to minimize these risks
Extensive persistent inflammation even when SARS-CoV-2-infected cells are only sporadically present at late stages of COVID-19 (Schurink et al., 2020) could also justify low GSH levels in association with over-abundance of cellular ROS, cellular oxidative damage, increased inflammation and cell death pathways activation seen in inflammaging (Zuo et al., 2019
In the former, presence of non-neutralizing antibodies contributes to increased infections whereas the latter can lead to life-threatening allergic inflammations 64,65
