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Acknowledgements This work was supported by National Key Research and Development Program of China (2021YFC2101500), the National Natural Science Foundation of China (31730004), and the General Program of Shanghai Natural Science Foundation (19ZR1413700)

DNA Repair & Epigenetic Modulation: Upregulates genes associated with tissue repair, youthfulness, and cellular longevity

Retatrutide acts via cell-surface incretin and glucagon receptors, whilst 5-Amino-1MQ works intracellularly by modulating enzyme activity and NAD+ metabolism