The only defense is to state the split explicitly at the top of every calculation and carry the per-component number all the way through, rather than reasoning about the peptide as if the vial held one substance
J Physiol Pharmacol 65(3):349357 Nozu T, Miyagishi S, Kumei S, Nozu R, Takakusaki K, Okumura T (2018) Glucagon-like peptide-1 analog, liraglutide, improves visceral sensation and gut permeability in rats
The good news is that most are mild and dont last long, and being prepared helps you manage them with confidence
CMD studies are more invasive than serum collection, limiting large scale sampling, generalizability of conclusions and increasing the impact of study design discrepancies (sample collection times, outcome follow-up, etc.) on reported values [28]