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Based on the typical UK regulatory pathway, the most realistic timeline is: Late 2026 / early 2027: Eli Lilly expected to submit regulatory filings to the FDA and MHRA following completion of the remaining TRIUMPH Phase 3 readouts Late 2027 to mid-2028: Possible MHRA marketing authorisation, allowing private UK prescribing 2028 to 2029 onwards: Possible NHS availability following a NICE technology appraisal and NHS commissioning decisions Timelines may differ across the four UK nations, as Scotland, Wales, and Northern Ireland assess medicines separately through the Scottish Medicines Consortium (SMC), All Wales Medicines Strategy Group (AWMSG), and the Department of Health Northern Ireland respectively

51 Airflow restriction is a critical part of COPD pathogenesis and is closely related to the proliferation and migration of airway smooth muscle cells and the secretion of inflammatory factors

These symptoms typically develop gradually over weeks, making them easy to dismiss, but they warrant a simple blood test measuring serum ferritin, iron, and hemoglobin levels

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