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When to Discard a Vial You should consider discarding your semaglutide if: You are past the BUD printed on the label The solution looks cloudy, discolored, or has particles The vial has been left at room temperature too long or frozen You suspect microbial contamination (e.g., off odor, visible changes) When in doubt, its safer to dispose of it and request a fresh vial your safety and treatment effectiveness matter most

The first sign of degradation is a color shift from clear pale blue to greenish-brown, followed by haze or visible particulate