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The simultaneous interaction with the endogenous Ub-E2-E3 complex and the protein of interest results in the generation of an Ub-E2-E3-neosubstrate complex, ultimately leading to ubiquitinylation and degradation of target protein

Route of Administration : The choice of a buffer is also influenced by the intended route of administration

This is an important question because we know that being exposed to a virus, whether one recovers or not, can have profound effects on the immune system with certain pathogens