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Sublingual delivery improves absorption marginally but still subjects the compound to first-pass hepatic metabolism and enzymatic degradation before systemic circulation

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The Benefits Even if you dont suffer from a deficiency, a B12 boost can still provide a number of benefits, from reducing the risk of deficiency-related conditions to improving brain function, bone health and giving you an overall energy boost: Reduced risk of associated complications Even if you arent showing pressing signs of a B12 deficiency, many of us still arent getting the right volume every day, particularly if were sick, pregnant or breastfeeding

10.1016/s0140-6736(11)61452-9 Lancet 158 RaymanM