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Against this background, access to innovative therapies should not be viewed merely as a question of improving quality of life

Because they are structurally similar to proteins, they are vulnerable to digestive enzymes in the stomach and gut, and they require either injection to bypass the digestive tract entirely, or a chemical absorption enhancer called salcaprozate sodium (SNAC) that transiently raises local gastric pH and enables brief absorption through a narrow window which is why the Wegovy pill must be taken on an empty stomach followed by a 30-minute fast

However, they commonly cause gut side effects like indigestion, nausea, vomiting and diarrhoea

A 4-year trial of tiotropium in chronic obstructive pulmonary disease