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The transgene carrying this 3UTR replacement was otherwise identical to the sygl-1 transgene described above ( Fig 1C ), including insertion into the same chromosomal site and rescue of lst-1 sygl-1 double mutants from sterility to fertility ( S3A Fig )

Subcutaneous injection places the solution into fatty tissue beneath the skin using a sterile needle technique

GLP-1 medications like Zepbound and Wegovy deliver stronger weight loss results, carry fewer concerning side effects than the stimulant-based approach of a weight loss medication like Qsymia, and offer meaningful cardiovascular and metabolic benefits beyond weight reduction

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