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The nonBWS livers exhibited normal methylation at both IC1 and IC2, while the BWS samples were either IC2 LOM ( n = 2) or pUPD11 ( n = 2), consistent with clinical testing results in blood (Supplementary Table 1)

35(Suppl

Another indirect effect of temperature is the dissociation constant of water: The hydroxyl ion concentration of water can vary as a function of temperature and thereby affect deamidation rates (39)