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Recent findings reveal that disruptions in Hcy metabolism, coupled with deficiencies in vitamin B12 along with folate can alter methylation as well as redox states, ultimately impacting calcium influx and contributing to the accumulation of amyloid and tau proteins

Moreover, a decline in Bifidobacterium species has been proposed to be associated with abnormalities in central pain processing via the gutbrain axis [94]

Whilst often discussed alongside GLP-1 receptor agonists such as semaglutide and liraglutide, Mounjaro is technically a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist