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If you suspect a deficiency a clinician can run simple blood tests and advise whether targeted supplementation makes sense

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People taking retatrutide, a drug being developed by Eli Lilly, lost an average of more than 70 pounds, or 28.3% of their bodyweight, over the course of 80 weeks, according to the company's preliminary report of clinical trial results

The SER/5-HTP ratio was not different between patients and controls, while the 5-HIAA/SER ratio was significantly higher in patients compared to controls (p = 0.031) ( Figure 3 )