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SOD is an important component of the bodys antioxidant defense system, protecting cells from free radicals and, consequently, oxidative stress [35]

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These changes included a decrease in the proportions of Firmicutes / Bacteroidota , indicating a potential disruption of gut microbiota balance ( Muribaculaceae and Alloprevotella genera are related to the intestinal inflammation, barrier dysfunction, as well as glucose and lipid metabolism, further emphasizing the role of these oral pathogens in systemic diseases ( However, the variations in gut genera associated with TMAO remain unclear, which is consistent with previous reports, perhaps due to standard diet we used