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5,6 Interestingly, in vitro studies of liver cancer cells have demonstrated that GLP-1RA medications can have a direct effect on hepatocellular carcinoma (HCC) through the regulation of tumor suppressor or proto-oncogenes and induce cell cycle arrest, autophagy, and senescence in cancer cells

Since these preclinical and clinical studies are still in the early stages, firm conclusions about which patient groups may respond best remain undetermined

Companies developing high-quality biosimilar GLP-1 therapies with competitive pricing and proven bioequivalence will democratize access while capturing significant market share in cost-sensitive segments