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For early-stage blood sugar management without significant obesity, metformin alone often suffices

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5.1 Mediterranean diet The traditional Mediterranean diet (MeDiet), recognized by the United Nations Educational, Scientific and Cultural Organization as an Intangible Cultural Heritage of Humanity, is characterized by a complete, minimally processed plant-based diet (cereals, legumes, vegetables, fruits, and nuts), small amounts of meat, milk, and dairy products, and moderate amounts of red wine, nuts, olive oil, and fatty fish (Figure 3A) (111, 112)

Collectively, these studies demonstrate that nutrients seem to partially drive the transcriptional machinery in taste cells with consequences on food intake