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Pyridoxine: Vitamin B6 for Metabolism and Mood Pyridoxine, or vitamin B6, is involved in amino acid metabolism, neurotransmitter production, and red blood cell formation

313,314,315,316,317 Consistently, several established animal models of ASD, including the naturally occurring BTBR strain ( Bifidobacterium and Blautia flora ), MIA model offspring ( Clostridium ), 318,319 VPA-treated rodents ( Desulfovibrionales ) 320,321 and mice lacking the synaptic adhesion protein SHANK3 ( Lactobacillus reuteri ), 322,323 all show disturbance of the intestinal flora

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