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Effectiveness may depend on multiple factors including adherence to the prescribed plan, dietary and lifestyle choices, individual metabolism, pre-existing health conditions, and psychological well-being

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The investigators interpreted the effects as direct pharmacological validation of the NNMT-knockdown phenotype reported earlier in genetic models

Fortunately, there are new obesity treatments available called glucagon-like peptide 1 (GLP-1) receptor agonists, which can help people lose 15% of their body weight over the course of a year when paired with healthy lifestyle changes