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These have the strongest clinical evidence for meaningful body-weight reduction

Rice D, Barone S (2000) Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models

For example, IAV infection triggers mtDNA release via mitochondrial permeability transition pore (mPTP) opening, activating cGAS-STING signaling and promoting type I IFN responses (Moriyama et al., 2019)

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