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Understanding the FDA's Compounding Category System For non-clinical readers, the three-tier classification is worth spelling out plainly: Category 1 substances can be legally compounded by licensed 503A pharmacies (individual prescription-based) and 503B outsourcing facilities (larger-scale production)

Using this cream with other strong topical products such as prescription retinoids (e.g., tretinoin), chemical exfoliants (alpha- or beta-hydroxy acids), or benzoyl peroxide may increase irritation

MSH-derived tripeptide that suppresses inflammatory cytokines and provides antimicrobial protection

Apparently, no other signaling system is able to compensate for a lack of the c-Met in this process