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Muscle wasting, poor muscle tone, and weakness As a therapy for people with HIV, tesamorelin plays double duty as a countermeasure against another common symptom of the disease: wasting.15 Defined in part as the loss of more than 10% of a persons body weight, HIV-associated wasting is thought to stem from various aspects of HIV infection and treatment low appetite, altered metabolism, poor nutrient absorption, opportunistic infections, depression, drug side effects, and inflammation.16 Its a serious consequence but one that can be mitigated

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[DOI] [PMC free article] [PubMed] [Google Scholar] 434.Zhang H., Sturchler E., Zhu J., Nieto A., Cistrone P.A., Xie J