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Dogs received two cups of HFHF canine diet per day, with feeding 3 h postdose during the 14-day study

Finally, we moved in vivo, and observed that systemic treatment with a potent GGT inhibitor decreases the growth of tumor xenografts

Taken together, docking analyses suggest that neuromedin C engages GLP-1R through an interaction architecture resembling that of GLP1 and other peptide agonists, while remaining fundamentally distinct from the compact TM-centered binding patterns typical of non-peptidic ligands

Both nutrients exert antidepressant effects through gut microbiota regulation, either by enhancing SCFA production or reducing inflammation, making them the most promising candidates for clinical translation (consistent with Sections 4.3, 5.3)