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Finally, if menstrual changes are accompanied by other concerning symptoms such as significant mood disturbance, hot flushes suggesting premature ovarian insufficiency, or signs of androgen excess including excessive hair growth or acne, arrange a comprehensive hormonal assessment with your GP, who may refer you to an endocrinologist or gynaecologist for specialist evaluation and management

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No antibody formation When the immune system recognizes a foreign protein and produces antibodies against it, this can reduce the compound effectiveness over time and potentially cause allergic reactions

Documentation should clearly justify why an injection was required