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Now, recent studies and clinical trials have found that these drugs also have health benefits beyond weight loss, potentially paving the way for broader insurance coverage and thus wider-access

Sampedros team ( 4.4 Long-term safety and off-target effects Emerging reports link GLP-1RAs to rare ocular adverse events, including NAION ( 5 Conclusion In conclusion, the expanding body of evidence supports that GLP-1RAs offer a multifaceted approach to ocular therapeutics by targeting key molecular pathways involved in retinal neuroprotection, mitochondrial regulation, inflammation, vascular remodeling, and angiogenesis

Of course, weak efficacy and poor safety profile played a key role here

AstraZeneca in CVRM Cardiovascular, Renal and Metabolism (CVRM), part of BioPharmaceuticals, forms one of AstraZenecas main disease areas and is a key growth driver for the Company