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Our experience working with research protocols shows consistent patterns: morning-dosed subjects demonstrate faster senescence marker reduction and lower residual peptide concentration in serum at 24-hour follow-up, indicating superior cellular uptake rather than prolonged circulation

To further assess the varying relationship of metabolites with eGFR we computed boosted trees models predicting eGFR with serum metabolomics as the input variable, with a similar methodology to TMAO

These findings suggest that, while TS and GABA treatment alters gut microbiota, GABA treatment may alleviate aberrant alterations in the TS-induced gut microbiota

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