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Liver Enzymes In a pediatric clinical trial, increases in alanine aminotransferase (ALT) greater than or equal to 5 times the upper limit of normal were observed in 4 (3%) WEGOVY-treated patients compared with 0% of placebo-treated patients

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The transcriptional signatures identified in GLP-1MK-801-treated animals were enriched for functional terms related to synaptic transmission, such as postsynaptic density and glutamatergic synapse (Fig