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84,85,86 Most cancer cells overexpress IDO, and the level of kynurenine in the microenvironment is associated with poor prognosis in multiple solid and hematological malignancies

Neuroprotection by transgenic expression of glucose-6-phosphate dehydrogenase in dopaminergic nigrostriatal neurons of mice

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Safety Research Priorities Comprehensive long-term safety studies are critically needed, particularly given concerns about potential effects on cancer development and progression