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Lancet Glob Health 5(12):e1221e1234 Das S et al (2022) Innate immunity dysregulation in aging eye and therapeutic interventions

Prior to the commencement of experiments, these mice underwent an acclimatization period of one week under laboratory conditions

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Also, pentadecapeptide BPC 157, given peripherally, could affect sphincter function through serotonin (51, 52) or dopamine (in the same dose-range that BPC 157 prevented/reversed catalepsy or stereotypy and all concomitant gastrointestinal lesions) (53-56), likely providing a particular balance between peripheral and central effects (57)