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These hormones, which are mainly glucagon-like peptide-1 (GLP-1), cholecystokinin (CCK), peptide YY (PYY), gastric inhibitory polypeptide (GIP) and ghrelin, influence the functioning of the digestive tract, but also modulate insulin secretion from the pancreas, the energy storage of adipose tissue and neuronal signalling in appetite centres in the brain to mediate the regulation of food intake by terminating hunger and inducing satiety

A lo largo de ese tiempo se ha observado que, junto con una dieta baja en caloras y aumento de la actividad fsica , la prdida media de peso que producen oscila entre el 8%, en el caso de Saxenda, y el 18% de media, de las diferentes dosis posibles de Mounjaro

Hupfeld KE, McGregor HR, Lee JK, Beltran NE, Kofman IS, De Dios YE, et al