semaglutide recombinant synthesis CN115322250A - method of A Sustainable Chemo-Enzymatic Approach to

semaglutide recombinant synthesis

semaglutide recombinant synthesis CN115322250A - method of A Sustainable Chemo-Enzymatic Approach to

Name: semaglutide recombinant synthesis CN115322250A - method of A Sustainable Chemo-Enzymatic Approach to
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Description

The solubility of semaglutide changes with pH

DNA polymerase was used for the PCR amplification ( Figure 2)

the fermentation may be carried out in fed-batch to produce expressed semapeptide

By creatively splitting 31 amino acids of a main peptide chain of the semaglutide are into a 3-site amino acid polypeptide chain (MI chain) and a 28-site amino acid polypeptide chain (MII chain), the possibility of efficiently and quickly preparing the semaglutide under an escherichia coli preparation system is realized