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Extended activity: Reduced binding-protein affinity gives a longer half-life than native IGF-1, the analogs defining feature [2]

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Together, these signaling systems provide a framework for investigating how angiogenic signaling, cytoskeletal organization, and fibroblast-mediated extracellular matrix processes interact in laboratory models of tendon, ligament, and musculoskeletal tissue biology

Mayatepek E, Okun JG, Meissner T, Assmann B, Hammond J, Zschocke J, Lehmann WD: Synthesis and metabolism of leukotrienes in gamma-glutamyl transpeptidase deficiency