Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1
Mller TD, Finan B, Bloom SR, DAlessio D, Drucker DJ, Flatt PR, Fritsche A, Gribble F, Grill HJ, Habener JF, Holst JJ, Langhans W, Meier JJ, Nauck MA, Perez-Tilve D, Pocai A, Reimann F, Sandoval DA, Schwartz TW, Seeley RJ et al (2019) Glucagon-like peptide 1 (GLP-1)
Alongside a healthy, active lifestyle and well-rounded diet, though, appetite suppressants can be a very helpful tool for certain individuals looking to change their relationship with food
These effects usually develop within the first few weeks of treatment but may diminish slightly over time as physiological adaptation occurs