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In this sense, Ma et al

This essential endogenous antioxidant, which cells make, actively contributes to the elimination of free radicals and reactive oxygen species [6]

The residue A263 from the I domain, situated at the buried interface and close to the specificity-determining loop (SDL) of the molecule, makes a strong H-bond between its backbone carbonyl oxygen and the 25-OH group of 25HC

Vegetarian sources of B12 include chlorella, nori, nutritional yeast and certain mushrooms, but many vegans and vegetarians have insufficient levels of B12 because its not widely found in plants. According to Mullane, not getting enough B12 can result in issues like anaemia, fatigue and more intense symptoms including shortness of breath, palpitations, pale skin, muscle weakness, numbness and tingling in hands or feet, blurred vision and memory loss