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The combination of quercetin and dasatinib may specifically induce apoptosis of senescent TECs, therefore restoring renal function and ameliorating fibrosis ( In vivo study has revealed that senolytic therapy of quercetin and dasatinib improved renal artery stenosis by reducing the p21 positive stenotic TECs and attenuating mesenchymal transition ( 4.5 Other renal disorders Dietary intake of the flavonoid quercetin has been proven effective in lowering blood pressure and restoring endothelial dysfunction in animal models of hypertension

Endoplasmic reticulum stress and oxidative stress in cell fate decision and human disease

& Adrover, M