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[19] [20] New or progressive neurological symptoms following nitrous oxide exposure warrant urgent medical assessment

Similarly, low doses of the PARP inhibitor olaparib can reduce the immunosuppressive activity of MDSCs by downregulating arginase-1 (ARG1) and iNOS, thereby restoring the activity of CTLs

If any of these signs or symptoms occur, it is important that the patient is evaluated promptly and the dose of this formulation is adjusted accordingly