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However, the possibility of a placebo effect can only be completely ruled out by an RCT

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Precision biomarkers for women exposed to night shift work Emerging evidence underscores the urgent need to incorporate novel biomarkers to identify women who are particularly susceptible to the adverse effects of NSW, especially those at increased risk of developing BC or who already exhibit early biological signs of exposure-related harm 261

However, there is evidence from DoD commercialization data to suggest that despite relatively flat DoD Research, Development, Test and Evaluation (RDT&E) funding through the 1990s, a steadily increasing number of DoD Phase II SBIRs won follow-on sales/investment contracts