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Although there have been contradictions on the supplement's ability to promote loss of weight, a study carried out on obese individuals supported the claim that L-carnitine does aid weight loss [4]

The X-ray-derived data of small molecular fragments in complex with TGR used in this study to design the compounds here described are available in the PDB under accession codes 6FTC, 6FMU, 6FMZ, 6FP4, 2X99, 2X8G, 2X8H, 6ZST, 6ZP3, 6ZLP, 6ZLB, 7B02, 7NPX, 2V6O, 6RTJ, 6RTO, 6RTM, and 3H4K

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Clinical trials reported that the intake of some nutraceuticals (Hawthorn, Coenzyme Q10, L-carnitine, D-ribose, Carnosine, Vitamin D, Probiotics, Omega-3 PUFAs, Beet nitrates) is associated with improvements in self-perceived quality of life and/or functional parameters such as ejection fraction, stroke volume and cardiac output in HF patients, with minimal or no side effects