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Its also not recommended for use in some conditions, such as: Pregnancy Gastroparesis Inflammatory bowel disease Multiple endocrine neoplasia 2A or 2B Suicidal ideation What To Consider Before Starting Starting a new medication is a decision best made in partnership with your doctor, and there are factors to consider

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The contribution of tryptophan-derived niacin to niacin needs in the body varies widely and a few scientific studies have demonstrated that diets high in tryptophan have very little effect on niacin deficiency