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Although DHA may reduce estrogen synthesis via cyclooxygenase-2 inhibition, further studies using precise biomarkers of DHA exposure and controlling for obesity-related hormonal and inflammatory pathways are needed to clarify these inconsistencies and determine the direction of the association

Testosterone influences factors such as skin thickness, oil production, and hair growth, making men's skin naturally thicker and more prone to oiliness

A systemic review of 16 studies reported that specific irAEs like mucositis, pneumonitis, myalgias and thyroid disorders are not statistically correlated with OS [73]

Healthcare providers typically recommend an individualized duration for weight management