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Based on the oxidative stress hypothesis, oxidative damage is not solely triggered by the unrestricted ROS production, but it also caused by other oxidants, such as reactive lipid species and reactive nitrogen species (RNS)

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There are many risk factors involved in infertility issues but the main ones are the following: age fertility declines with age, weight being overweight or underweight, sexually transmitted infections (STIs), smoking, alcohol, STRESS, environmental factors, PCOS, endometriosis, and certainly genetics

Estradiol dynamics during weight loss in women treated with GLP-1 receptor agonists