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For a plain-language summary of growth hormone physiology and its role in body composition, sleep, and tissue repair, a peer-reviewed Nature Reviews Endocrinology paper examining the role of the growth hormone / IGF-1 axis in obesity, adult body composition, and metabolic regulation is a strong starting point

Additionally, other issues, like liver disease, might become aggravated by fluctuating thyroid hormone levels, even when the liver cells are capable of handling their own levels of oxidative stress