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August 2021: Ozempic Associated With Heightened Risk of Diabetic Retinopathy Study results focused on diabetic retinopathy (DR) in patients taking semaglutide found that a higher risk for DR complications were observed with semaglutide in patients with proliferative and non-proliferative DR at baseline. However, researchers do acknowledge that worsening DR can be from rapid drops in blood glucose levels from diabetic medications

The additional receptors in retatrutide increase metabolic rate, enhance fat breakdown, and reduce nausea while providing the same appetite suppression and gastric slowing as Ozempic

Some protocols recommend waiting longer, up to 2 weeks, particularly for patients transitioning from high tirzepatide doses (12.5 mg or 15 mg) to reduce the overlap of active drug and minimize initial side effects

Volek JS, Kackley ML, Buga A