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Caution and close monitoring are warranted in individuals with preexisting diabetic retinopathy, due to a higher incidence of retinopathy-related complications observed in clinical trials, particularly with semaglutide ( 4 Cardiovascular results 4.1 Evidence of SGLT2 inhibitors in patients with DM2 The management of DM requires a long-term perspective, emphasizing the importance of medication safety over time

Pharmacotherapy Considerations Older Adults Special care is required in prescribing and monitoring pharmacologic therapies in older adults

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The medicines, which include semaglutide and tirzepatide, are immensely popular across the United States and are now being used to help people get over addiction