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10 = severe], the rating should be no higher than a 1-2 depending on the sensitivity of the child

Its Phase 3a REDEFINE 1 and REDEFINE 2 trials are published and complete, but the product remains investigational while its benefitrisk profile is evaluated

On the other hand, the demonstration of paracetamol's progressive hepatic encephalopathy with severe seizures at least partly overruled the general discordance of NSAIDs' adverse effects and therapeutic application, paracetamol in particular as previously mentioned (1-10)