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By suppressing the expression or function of the Xc-system, PAB slows tumor growth in vivo , while also inhibiting cancer cell invasion and metastasis ( Ursolic acid, a pentacyclic triterpenoid derived from traditional plants, significantly boosts ROS accumulation in a hepatocellular model when paired with sorafenib ( Sodium butyrate demonstrates anti-cancer properties by modulating the GSH/GSSG ratio, intracellular ROS levels, and lipid peroxide content, thereby inducing ferroptosis in endometrial cancer cells

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Berberine has potential for drug interactions based primarily on in vitro studies showing effects on cytochrome P450 enzymes, particularly CYP3A4, CYP2D6, and CYP2C9