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Description

Rather than modulating the downstream tissue response, KPV intercepts inflammatory signaling at NF-kB before cytokines are produced, before the cascade amplifies

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Through activation of the Nrf2antioxidant response element (ARE) signaling axis, GSH upregulates cytoprotective enzymes such as heme oxygenase-1, glutathione peroxidase, and NAD(P)H quinone oxidoreductase-1, thereby enhancing cellular resistance to oxidative injury [10]

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Pharmacotherapy

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