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The bacterial lipopolysaccharide (LPS) is considered an endotoxin which upon reaching the host blood, it increases the release of pro-inflammatory cytokines that was observed to decrease the expression of L-type Ca 2+ channels and shorten effective refractory period (ERP) [12]

The Summary of Product Characteristics (SmPCs) for major GLP-1 agents authorised by the MHRA does not list erectile dysfunction among recognised adverse reactions