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Inhibition of the target gene expression can occur through various mechanisms such as RNA interference, once the sense-antisense mRNA duplex has formed, transcriptional interference, in which the NAT can act as a physical barrier for RNA polymerase activity, or epigenetic methylation of the sense gene DNA, thus inhibiting the transcription of the sense mRNA transcript [55, 56]

Doctors describe this as a unique situation whereby so many brands of the same medicine are set to be launched on the same day

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It is commonly used to target areas like the abdomen, thighs, and arms